منابع مشابه
Verapamil in Diabetes
Figure 1: Models of thioredoxin‐interacting protein action: (a) Role of thioredoxin‐interacting protein in the thioredoxin system. Thioredoxin‐interacting protein binds and inhibits the reduced form of thioredoxin, thereby functioning as a rheostat that modulates both redox status and reactive oxygen species‐mediated signaling to regulate metabolism and other cellular processes. (b) Proposed ro...
متن کاملClinical outcomes in the diabetes cohort of the INternational VErapamil SR-Trandolapril study.
The INternational VErapamil SR-Trandolapril study (INVEST) had 6400 of 22,576 (28.3%) participants with diabetes at entry. The objectives of this prespecified analysis were to compare antihypertensive treatment strategies in the diabetes cohort (verapamil SR-based [n=3169] versus atenolol-based [n=3231]) and identify predictors for the primary outcome (a composite of first occurrence of all-cau...
متن کاملVerapamil in primary pulmonary hypertension.
An 8 year old girl with primary pulmonary hypertension and signs of heart failure was given 17.5 mg of verapamil injected into the pulmonary artery over 25 minutes to test for the reversibility of pulmonary arteriolar obstruction. Pulmonary artery pressure fell from 70/50 to 35/25 mm Hg. Treatment with 40 mg verapamil by mouth four times daily was started, and she was discharged. She gradually ...
متن کاملProtective Effects of Verapamil Against Hexachlorobutadiene Nephrotoxicity in Rat
Background: Hexachlorobutadiene (HCBD), a potent nephrotoxin can cause degeneration and necrosis in renal tubular epithelial cells in rodents. Its toxicity is due to conjugation with glutathione to form the related cysteine conjugate. This metabolite is then taken up by the kidney and cleared through renal tubular epithelial cells as a reactive thiol derivative by the enzyme β-lyase. Objective:...
متن کاملStercoral perforation with verapamil.
Sir, Constipation is the commonest and most troublesome non-cardiac side effect of verapamil use.', We would like to report a case of stercoral perforation in a woman taking verapamil. A 78 year old woman was admitted with sudden onset of lower abdominal pain associated with signs of generalized peritonitis. She had developed chronic constipation after commencement of verapamil for recurrent su...
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ژورنال
عنوان ژورنال: Indian Journal of Endocrinology and Metabolism
سال: 2017
ISSN: 2230-8210
DOI: 10.4103/ijem.ijem_190_17